Downstream Scientist

Posted 27 Nov 2019

Shanghai - all, Shanghai - China

Req Id 200153


A career at our company is an ongoing journey of discovery: our around 52,000 people are shaping how the world lives, works and plays through next generation advancements in healthcare, life science and performance materials. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others.

Position Title

Downstream Process development Scientist

Requested Role


Reporting to

DSP&ANA Manager

Requested Role Code


Position holder


Position holder MUID











In projects




Turnover €


Budget €


Reason for request

New position

Significant change in position (please specify)


Specific Job Description

Key Accountabilities

Downstream technical

  1. Design and optimization of anti-antibody downstream process
  2. Deal with the issues in process development by logical method
  3. Adjust the corresponding experiment plan according to the experimental data
  4. Process transfer to other departments or customers
  5. To organize and maintain all kinds of table account, include equipment account, material account, sample account and so on
  6. Record and behavior follow the compliance with laws, regulations and SOPs.
  7. Accept internal training such as (SOP of equipment and method) and perform training to scientist (method, platform).


  1. Reasonable arrangement the timeline of project, delivery process on time
  2. Drafting project protocol and report
  3. Present project schedule and update the project to client following requirement

Lab work

  1. Follow up material and consumable inventory to meet the projects requirement and quality, review the logbook of in/out bound
  2. Ensure assigned equipment validation, calibration and maintenance are done and documented as scheduled.
  3. Cooperate to prepare and update PD area and pilot area SOPs and other documentation as needed to support client projects and internal activities
  4. Ensure the work area is safe and clean. Keep up to date with Health and Safety regulations,


Other works assigned by manager





Strategic Impact







Candidate’s Profile


  • Master of Science Degree or above, Major in Biochemistry, Chemical Engineering, Biotechnology, Bioengineering, Pharmacy or equivalent


Work Experience

  • Deeply understand downstream process product (resins, filters, membranes, columns)
  • Familiar with protein analysis tool, use the tools to understand protein information.
  • Good sense of scale up, including the theory, material calculation and preparation
  • > 5 years downstream process development and optimization working experience in biologics or biopharmaceutical industry
  • Team spirit and respectful behavior
  • Strong sense of responsibility and professionalism


Job specific Competencies & Skills


Comparable Positions within Merck


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What we offer:  With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!

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