Research and Development Scientist

Posted 31 Jul 2020

St. Louis, Missouri - United States

Req Id 208782


A career with MilliporeSigma is an ongoing journey of discovery: our 57,000 people are shaping how the world lives, works and plays through next generation advancements in healthcare, life science and performance materials. For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.

MilliporeSigma is building a new Novel Modalities R&D department to support cutting edge APIs in the pharma industry.  With this new team, we will develop and provide the manufacturing platform for life saving drugs.


Your role:

We are hiring an R&D Scientist for our newly created Novel Modalities R&D organization.  Reporting to the Head of Novel Modalities R&D, the R&D Scientist will develop innovative manufacturing technologies or analytical methods for bioconjugates or RNA liposomes. 


  • Work with Principal Scientists or Senior Scientists to develop manufacturing technologies or analytical methods for bioconjugates or RNA liposomes.
  • Understand challenges in the contract manufacturing industry and work to ensure MilliporeSigma is on the cutting edge of bioconjugation or liposomes.  
  • Keep updated on product and industry knowledge and “best-in-class” manufacturing and analytical technologies
  • Demonstrate attention to detail in the execution and documentation of experimental work
  • Establish a team-based approach with other internal organizations, such as marketing, sales, PAD, QC and operations.
  • Provide timely and comprehensive written and oral communications to the team


Who You Are: 
Minimum Qualification:

  • Bachelor’s degree in Chemistry, Chemical Engineering, Biochemistry, Biology or other related Scientific discipline with 3+ years laboratory experience
  • 2+ years of R&D experience
  • 2+ years’ experience of preparation process or analytical techniques for bioconjugates or liposomes
  • 2+ years’ experience with process instruments (AKTA, UFDF) or analytical instruments (HPLC or GC or particle characterization)


Preferred Qualifications:

  • PhD or Master’s degree with 1+ years of ADC or liposomes industry experience
  • Experience in CMO or CRO
  • Working experience in cGMP/GLP, knowledgeable about ICH and FDA guidelines
  • Hands on experience in analytical method development and method transfer for Analytical Scientist or hands on experience in technology transfer and scale-up to manufacturing process in the contract manufacturing industry for Process Scientist
  • Experience with advanced data analysis and/or statistical software systems is a plus
  • Experience with gene therapeutics is a plus
  • Knowledge of process or analytical techniques in molecular biology is a plus.
  • PAT and Automation (medium to high throughput) experience in analytical is highly desirable
  • Excellent written and verbal communication skills
  • Working knowledge of Microsoft Office


What we offer: With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!

Curious? Apply and find more information at

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

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