Manufacturing Supervisor - Night Shift

Posted 12 Jan 2024

St. Louis, Missouri - United States

Req Id 271036


Work Your Magic with us!  Start your next chapter and join MilliporeSigma.


Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  


This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 


Your role:


At MilliporeSigma, as the Manufacturing Supervisor – Night Shift, at our Dekalb facility/ 3500 Dekalb Street, St. Louis, you will oversee the off-shift operations of 24/5 (Sunday night-Friday Day) large-scale protein manufacturing in a Process Safety Management (PSM) environment.   You will lead a team of scientists and operators to manufacture products according to established protocols while following the site safety and quality guidelines.


  • Shift is from Sunday – Thursday  6:30pm – 3:00am
  • Maintain a regimented schedule to meet product release deadlines
  • Support the floor operations when needed
  • Set metrics for the team based on the department and site goals
  • Understand and follow budgetary guidelines
  • Interface across departments to accomplish tasks
  • Review final assays and procedures to ensure products are meeting the quality guidelines
  • Write and modify SOPs or product processes consistent with quality guidelines and review other procedures as requested
  • Identify opportunities for process improvement
  • Take the necessary action to resolve any unsafe conditions through proper escalation and seeking support
  • Evaluate the risks and cost effectiveness to the supply chain
  • Independently investigate, identify current inefficiencies and implement improvements
  • Train personnel and act as a technical lead.
  • Perform and interpret analytical evaluations of products
  • Maintain a high throughput overnight as part of 24 hour operations

 Physical Attributes:

  • Lift, push, pull or move up to 50 lbs
  • Wear appropriate PPE such as masks, safety shoes, protective gloves, safety goggles


Who You Are:


Basic Qualifications:


  • Bachelor’s Degree in a life science discipline (e.g., Chemistry, Biochemistry, Biology, Chemical Engineering)  with 3+ years of life science manufacturing leadership  


  • High school diploma or GED with 5+ years of life science manufacturing leadership


Preferred Qualifications:


  • Knowledge in chemistry or biochemistry, math and general science
  • Familiar with laboratory instruments and large-scale production equipment (reactors, pumps, large tanks, centrifuge, filter press, etc.)
  • Safe chemical handling methods.
  • Communication skills, oral and written.
  • Computer skills; Word, Excel, Powerpoint
  • Mechanical and Troubleshooting skills.
  • Interpersonal and organizational skills
  • Laboratory and analytical skills.
  • Knowledge of ISO Quality standards and Process Safety Management (PSM).
  • Operational Excellence methodologies
  • General understanding of business finance practices

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of our diverse team!


If you would like to know more about what diversity, equity, and inclusion means to us, please visit

US Equal Employment Opportunities

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

We are committed to an equitable hiring process for candidates from a diverse range of backgrounds. As part of this commitment, applicants with disabilities may be entitled to reasonable accommodations. Please contact, if a reasonable accommodation is needed or if you otherwise need assistance to participate in the hiring process.

North America Disclosure

If you are a resident of California, Colorado, New York, or Washington, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.

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