Sr. Scientist

Posted 16 Apr 2024

St. Louis, Missouri - United States

Req Id 272858


Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

Your Role:

As a Senior Scientist,  you will work in a project-focused environment as a member of a multidisciplinary Process Development (PD) group responsible for development and qualification of manufacturing methods to support new product introduction and optimization of existing processes.

Responsibilities include: to design and perform laboratory experiments and evaluate data to ultimately develop reliable manufacturing and/or QC methods, perform and troubleshoot initial processing of newly developed and/or scaled up procedures with the relevant Operations teams to qualify new methods, aid in training and transfer of newly developed methods to the manufacturing team, write manufacturing procedures for Operations’ use, apply Root Cause Analysis tools to troubleshoot manufacturing issues, design and develop new products for customers in the life science field, develop manufacturing processes that may require the following:  Fermentation / cell culture, extraction of proteins from plant, animal, or bacterial sources, and protein purification.


Who You Are: 

Minimum Qualifications:

  • Master’s Degree in a scientific discipline (e.g., Biochemistry, Molecular Biology, Chemistry, etc.)
  • 5+ years of experience in independent lab research or chemical manufacturing


Preferred Qualifications:

  • Experience with protein purification and characterization, chromatography (IEX, HIC, SEC, etc.), enzymatic assay, recombinant protein expression, and/or microbial cell culture 
  • Experience with microbial genetics, molecular cloning techniques, and standard molecular biology techniques
  • Experience with culturing yeast or other non-E. coli microbes 
  • Experience with automated chromatography systems (such as GE AKTA) and bioreactors / fermenters (such as Sartorius BIOSTAT)


What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of our diverse team!


If you would like to know more about what diversity, equity, and inclusion means to us, please visit

US Equal Employment Opportunities

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

We are committed to an equitable hiring process for candidates from a diverse range of backgrounds. As part of this commitment, applicants with disabilities may be entitled to reasonable accommodations. Please contact, if a reasonable accommodation is needed or if you otherwise need assistance to participate in the hiring process.

North America Disclosure

If you are a resident of California, Colorado, New York, or Washington, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request. You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.

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