* This program is not open to U.S. healthcare professionals.
Boost the therapeutic potential of your compounds
Through our Open Compound Sourcing initiative, we invite potential partners to submit their compounds to be included in our high throughput screening library and utilized in efforts to identify new therapeutics.
We’re looking for new organic chemical compounds to test in our screening campaigns for potential therapeutic activity. Your compounds would be tested against several targets and disease models. In case of a match, your specific compounds could become the next new chemical entity (NCE) or a starting point for further optimization in one of our strategic therapeutic areas of focus: Oncology, Immuno-Oncology as well as Autoimmune Disorders. You will keep all rights to your compounds and in case of interest, we will offer you a follow-up collaboration agreement.
Who can apply?
Merck KGaA, Darmstadt, Germany, invites universities, research institutes and private companies to register with us to participate in the Open Compound Sourcing Initiative. After registration, participants will sign a “Participation and Material Supply Agreement (P&MSA)”. The agreement will cover the legal, intellectual property and commercial aspects of transferring your organic compounds to Merck KGaA, Darmstadt, Germany.
This program is not open to U.S. healthcare professionals.
How does it work?
After having a P&MSA in place, we screen your compounds in-silico. We therefore need the compound structure as SD-file (find more information about the SD file format in our FAQs). In a second step, we will ask you to provide the compounds selected based on the in-silico
screen. These compounds would then be included in the screening library for pharmaceutical activity testing. In case of hits, we will contact you to discuss the potential follow-up collaboration.
Your benefits
For each compound accepted for inclusion in our screening library, participants will receive €100 per compound.
If a compound qualifies as a hit during our screening campaigns, participants will be further compensated according to the terms of the P&MSA. At that time, participants will be contacted about partnership opportunities.
By participating in our Open Compound Sourcing, your molecule could become a much-needed therapy, helping to transform the lives of patients with serious unmet medical needs, or a promising starting point for further chemical optimization to achieve that goal.
How to apply
Please contact us to request the P&MSA document. You will then be asked to fill out and submit the P&MSA document via e-mail. We will then review the document and contact you regarding next steps for compound provision. Before registering, please read the FAQ below.
FAQs
Boost the therapeutic potential of your compounds
Through our Open Compound Sourcing initiative, we invite potential partners to submit their compounds to be included in our high throughput screening library and utilized in efforts to identify new therapeutics.
We’re looking for new organic chemical compounds to test in our screening campaigns for potential therapeutic activity. Your compounds would be tested against several targets and disease models. In case of a match, your specific compounds could become the next new chemical entity (NCE) or a starting point for further optimization in one of our strategic therapeutic areas of focus: Oncology,and Immuno-Oncology as well as Autoimmune Disorders.. You will keep all rights to your compounds and in case of interest, we will offer you a follow-up collaboration agreement.