Christina Carbrello

As a scientist, it is both fun and rewarding to tackle a tough technical challenge and eventually see all of the pieces fall into place.

Perspective

I like to solve puzzles.  I never fail to be amazed by the way the world works.  As a scientist, it is both fun and rewarding to tackle a tough technical challenge and eventually see all of the pieces fall into place.  It is especially fun to work on these challenges with an intelligent and dynamic team that bring different ideas and expertise to the table, enabling us to figure things out that each of us could not do on our own.  

As a scientist, it is both fun and rewarding to tackle a tough technical challenge and eventually see all of the pieces fall into place.

Christina Carbrello

Principal Scientist

Profile

Joined Merck KGaA, Darmstadt, Germany: 2005

Key research fields and topics:

  • Virus filtration, membrane formation, membrane structure function relationships

Prizes and awards:

  • Millipore Technical Innovation Award

CV & Scientific activities

CV: Education

CV: Education

CV: Professional Career

CV: Professional Career

Memberships

Memberships

References

Publications

  • H. Nazem-Bokaee, F. Fallahianbijan, D. Chen, S.M. O’Donnell, C. Carbrello, S. Giglia, D. Bell, A.L. Zydney, “Probing pore structure of virus filters using scanning electron microscopy with gold nanoparticles”, Journal of Membrane Science 552 (2018), 144-152
  • W. Fu, C. Carbrello, X. Wu., W. Zhang, “Visualizing and quantifying the nanoscale hydrophobicity and chemical distribution of surface modified polyethersulfone (PES) membranes” Nanoscale, 9(40), 2017, 15550-15557
  • F. Fallahianbijan, S. Giglia, C. Carbrello, A.L. Zydney, “Use of fluorescently-labled nanoparticles to study pore morphology and virus capture in virus filtration membranes” Journal of Membrane Science 536 (2017), 52-58
  • H. Lutz, R. Wilkins, C. Carbrello, “Sterile Filtration Principles, Best Practices and New Developments” in Sterile Product Development: Formulation, Process, Delivery and Quality Challenges, P. Kolhe, M. Shah, and N. Rathore, eds., Springer, 2013
  • C. Bondy, C. Santeufemio “Analysis of fouling within microporous membranes in biopharmaceutical applications using latex microsphere suspensions” Journal of Membrane Science 349 (2010) 12-24 
  • C. Bondy, D. Siitari, T. Root, E. Lightfoot “Identification of Non-Idealities in Gel Electrophoresis”  Journal of Chromatograph A, 1080: (2005) 2-14 Jul 2005
  • D. Lafarga, M. Al-Juaied, C. Bondy, A. Varma “Ethylene epoxidation on Ag-Cs/-Al2O3 catalyst:  Experimental results and strategy for determining kinetic parameters” Industrial and Engineering Chemistry Research  39: (7) 2148-2156  Jul 2000

Selected Presentations

  • “Fundamental Studies of Virus Capture in Virus Filtration Membranes”, poster presentation with F. Fallahianbijan, S. Giglia, D. Bell and A.L. Zydney, Recovery of Biological Products, Asheville NC, October 2018
  • “Evaluation of Filterability of Cell Culture Media Components Using Virus Filtration”, with S. Guidetti, J. Grayham, R. Karcher, Annual Meeting of the North American Membrane Society, Lexington KY, June 2018
  • “Defend Your Bioreactor:  Using Nanofiltration to Prevent Virus Contamination of Cell Culture Processes”, PDA Europe Virus and TSE Safety Forum, Dubrovnik, Croatia, May 2017
  • “Preventing Virus Contamination of Bioreactors with a Virus Barrier Filter” Bioprocessing Summit, Boston, Massachusetts, August 2015
  • “Overcoming Bacterial Retention and Capacity Issues in Adjuvant Filtration” World Vaccine Congress, Washington DC, April 2009
  • “Analysis of Fouling in Microporous Membranes in Biopharmaceutical Applications” poster presentation with C. Santeufemio, American Chemical Society National Meeting, Philadelphia, Pennsylvania, August 2008
  • “Identification of Non-Idealities in Two-dimensional Gel Electrophoresis” with Thatcher W. Root and Edwin N. Lightfoot, American Chemical Society National Meeting, San Diego, California, March 2005
  • “Developing a Quantitative Understanding of Two-Dimensional Gel Electrophoresis” with David W. Siitari, Thatcher W. Root and Edwin N. Lightfoot, Annual Conference of the American Electrophoresis Society, Austin, Texas, November 2004
  • “Modeling Electrophoresis to Improve Gel Reproducibility” with Thatcher W. Root and Edwin N. Lightfoot, Annual Conference of the American Electrophoresis Society, Indianapolis, Indiana, November 2002

 

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