On the occasion of its 350th anniversary, Merck KGaA, Darmstadt, Germany is initiating a competition to identify a CHO (Chinese Hamster Ovarian) cell line with most optimal antibody production yield. Anyone from around the world may register for the competition. From these applicants, Merck KGaA, Darmstadt, Germany will choose up to 12 candidates to participate in the challenge. These 12 candidates will be provided with the antibody expression construct and CHO cells. These candidates will then have 1 year to generate and submit a high expression CHO cell line. Submitted cell lines will be tested in a wet lab and the candidate providing the clone with the highest antibody yield will win a prize of EUR 20,000.