On the occasion of its 350th anniversary, Merck KGaA, Darmstadt, Germany is initiating a competition to identify a CHO (Chinese Hamster Ovarian) cell line with most optimal antibody production yield. Anyone from around the world may register for the competition. From these applicants, Merck KGaA, Darmstadt, Germany will choose up to 12 candidates to participate in the challenge. These 12 candidates will be provided with the antibody expression construct and CHO cells. These candidates will then have 1 year to generate and submit a high expression CHO cell line. Submitted cell lines will be tested in a wet lab to determine the antibody yield and to identify the most productive CHO cell lines. Based on that the gold (EUR 20,000), silver (EUR 10,000) and bronze (EUR 5,000) winners will be selected.