Programme

two-day session

The virtual event will be organized in two sessions (9th and 10th November 2020) from 16:00 to 18:00 CET to facilitate participation from colleagues overseas.
Each session will focus on a specific topic and will include two keynote talks followed by a round-table discussion. 

Monday 9th November 2020

Ternary PROTAC structures – essential or misleading for drug discovery?

Moderator: Dr. Ingo Hartung, Merck Healthcare KGaA, Darmstadt, Germany

16:00 - 16:10 Virtual conference opening and introduction
16:10 - 16:40 Dr. Alessio Ciulli (Univeristy of Dundee, UK) - Targeted protein degradation: how PROTACs work and why the ternary complex matters
16:40 – 16:50 Questions
16:50 - 17:20 Dr. Joe Patel (C4 Therapeutics, Watertown, MA) - Computational Methods for Degrader Ternary Complex Prediction Using HDX Data
17:20– 17:30 Questions
17:30 - 18:30 General discussion

Tuesday 10th November 2020

Protein structure prediction using machine learning

Moderator: Dr. Kristin Brown, GSK, Stevenage, UK

16:00 - 16:05 Introduction
16:05 - 16:35 
Dr. Mohammed AlQuraishi (Columbia University in New York, NY) - Nearly end-to-end differentiable learning of protein structure
16:35 – 16:45   Questions
16:45 - 17:15   Dr. David Baker (University of Washington, Seattle, WA) - Combatting coronavirus with de novo protein design
17:15 – 17:25   Questions
17:25 - 18:25   General discussion
18:25 – 18:30   Concluding remarks