The virtual event will be organized in two sessions (9th and 10th November 2020) from 16:00 to 18:00 CET to facilitate participation from colleagues overseas.
Each session will focus on a specific topic and will include two keynote talks followed by a round-table discussion.
Monday 9th November 2020
Ternary PROTAC structures – essential or misleading for drug discovery?
Moderator: Dr. Ingo Hartung, Merck Healthcare KGaA, Darmstadt, Germany
|16:00 - 16:10||Virtual conference opening and introduction|
|16:10 - 16:40||Dr. Alessio Ciulli (Univeristy of Dundee, UK) - Targeted protein degradation: how PROTACs work and why the ternary complex matters|
|16:40 – 16:50||Questions|
|16:50 - 17:20||Dr. Joe Patel (C4 Therapeutics, Watertown, MA) - Computational Methods for Degrader Ternary Complex Prediction Using HDX Data|
|17:30 - 18:30||General discussion|
Tuesday 10th November 2020
Protein structure prediction using machine learning
Moderator: Dr. Kristin Brown, GSK, Stevenage, UK
|16:00 - 16:05||Introduction|
|16:05 - 16:35
||Dr. Mohammed AlQuraishi (Columbia University in New York, NY) - Nearly end-to-end differentiable learning of protein structure|
|16:35 – 16:45||Questions|
|16:45 - 17:15||Dr. David Baker (University of Washington, Seattle, WA) - Combatting coronavirus with de novo protein design|
|17:15 – 17:25||Questions|
|17:25 - 18:25||General discussion|
|18:25 – 18:30||Concluding remarks|