two-day session
The virtual event will be organized in two sessions (9th and 10th November 2020) from 16:00 to 18:00 CET to facilitate participation from colleagues overseas.
Each session will focus on a specific topic and will include two keynote talks followed by a round-table discussion.
Monday 9th November 2020
Ternary PROTAC structures – essential or misleading for drug discovery? Moderator: Dr. Ingo Hartung, Merck KGaA, Darmstadt, Germany | |
|---|---|
| 16:00 - 16:10 | Virtual conference opening and introduction |
| 16:10 - 16:40 | Dr. Alessio Ciulli (Univeristy of Dundee, UK) - Targeted protein degradation: how PROTACs work and why the ternary complex matters |
| 16:40 – 16:50 | Questions |
| 16:50 - 17:20 | Dr. Joe Patel (C4 Therapeutics, Watertown, MA) - Computational Methods for Degrader Ternary Complex Prediction Using HDX Data |
| 17:20– 17:30 | Questions |
| 17:30 - 18:30 | General discussion |
Tuesday 10th November 2020
Protein structure prediction using machine learning Moderator: Dr. Kristin Brown, GSK, Stevenage, UK | |
|---|---|
| 16:00 - 16:05 | Introduction |
| 16:05 - 16:35 |
Dr. Mohammed AlQuraishi (Columbia University in New York, NY) - Nearly end-to-end differentiable learning of protein structure |
| 16:35 – 16:45 | Questions |
| 16:45 - 17:15 | Dr. David Baker (University of Washington, Seattle, WA) - Combatting coronavirus with de novo protein design |
| 17:15 – 17:25 | Questions |
| 17:25 - 18:25 | General discussion |
| 18:25 – 18:30 | Concluding remarks |