Shaping the future of healthcare
MEDICINE AS INDIVIDUAL AS PATIENTS
Our current approach to medical care is not working: Every patient – and his or her disease – is unique. Only some respond to general treatments. For example, today’s conventional, non-targeted drugs only work for one-third of all cancer patients, in three out of ten Alzheimer patients, and only half of patients with diabetes. That is why we need to radically alter our approach.
When the Human Genome Project was completed in 2003, it still cost 54 million US dollars to generate a human genome sequence. 12 years later, the costs for the same procedure were only 1,000 US dollars. In the last few years, the costs and duration of these procedures could be even further reduced. Rapid progress in the area of DNA sequencing and other technologies resulted in a real data explosion: They can be used to determine the exact molecular causes of diseases. For example, in 2003, only 1,474 genes with known disease-causing mutations had been identified. In 2015, 2,973 of such genes could already be identified. In 2003, there were only around 46 medicinal products with biomarkers on the market. 12 years later, this number had already risen to 132.
Did You Know?
Current untargeted drugs are ineffective in around three-quarters of all cancer patients.
In 2003, it cost $54 million to sequence one human genome. Twelve years later, it cost around $1,000.
In 2016, 28.3 million wearable devices were on the market but this will rise to 233 million by 2022.
HEALING WITH DETECTIVE PRECISION
However, in most cases, our genes only predict which diseases we might be susceptible to in the future – but ultimately, our real medical journey will be determined by the complex interaction of our genes, our lifestyle, and environmental factors. Scientists are therefore using highly advanced image processing and Omics technologies , combined with digital biosensors and mobile fitness and wellness equipment. This enables them to collect physiological and behavioral data on a large scale. This huge data volume can be combined and analyzed using artificial intelligence (AI) and machine learning. In future, these will help to identify subtle, yet measurable indicators of diseases.
Precision Medicine provides unprecedented potential for utilizing this continuously growing, increasingly precise information for medical screening, diagnosis and treatment of diseases – and for improving the health of every single patient. For implementation to be successful, various interconnected areas are necessary: the development of sophisticated tests which enable accurate diagnosis of a disease much earlier, a number of personalized preventative and delay measures, and a series of new drugs which are effective on molecular level and can treat an individual disease much more precisely and with less side effects.
HEALTH IS A MATTER OF THE HEART
We support people in each phase of their lives and help to create, improve, and extend life. We are discovering
and developing groundbreaking new ideas in oncology; in immunology, we have successfully provided new approaches for diseases such as multiple sclerosis in past and present, and today, we are one of the worldwide leading companies in the field of fertility treatment.
The following stories will tell how we are contributing to the future of medical care:
Imagine protecting yourself easily, efficiently and safely from the mosquitoes that transmit malaria. Our vision is to make this possible with IR3535®.
A tiny DNA motor that can detect viruses could help humanity to identify and deal with emerging threats faster.
A deeper understanding of the biology of MS opens new avenues to improve patient treatment.
DNA damage response
Drugs that block different DNA damage repair pathways could be used alone and together with chemo-, radio- and immunotherapy to transform cancer care.
Our new advanced 3D cell model is accelerating the search for new chemoprevention drugs that offer hope of eradicating the disease once and for all.
Drug delivery vehicles
Lipid nanoparticles (LNPs) underpin Covid-19 mRNA vaccines and are set to transform the future of medicine by delivering cutting-edge RNA therapeutics into cells.
Infectious diseases are one of the greatest threats to mankind. Our dream product Pandemic Protector could be a game-changer.
Data and digital health
By bringing the power of machine learning and artificial intelligence to solve medical problems, new digital health tools promise to revolutionize remote patient care.
Bioelectronic therapiesTiny electrodes that record and stimulate nerve activity could help to monitor and treat a wide range of diseases.DIVE DEEPER
Tomorrow's vaccinesThrough the TRANSVAC collaboration project, we're sharing our expertise to help speed up vaccine development and prepare for future pandemics.DIVE DEEPER
These smart drugs are already transforming cancer treatment. Could they be promising for other diseases too?
Additive manufacturing is normally used to make plastic or metal objects. Could the 3D printing of digital pills and living tissues radically change the future of medicine?
AI: supplying medicines
The healthcare supply chain ensures the right medicines are available to patients when they need them. Can artificial intelligence revolutionize this complex process?
AI helps fight NTDs
Find out how AI could potentially help improve diagnostics for two neglected tropical diseases, moving one step closer to their elimination.
Researchers are developing entirely new strategies based on bioorganic chemistry to fight multi-drug resistant germs - beginning a renaissance in antibiotic development.
Imagine you are living many kilometers away from your nearest doctor. Access to cloud-based healthcare could help change your life.
Improving drug testing?Organ-on-a-chip technologies offer a potentially powerful alternative for drug testing – helping to deliver new medicines to patients faster.DIVE DEEPER
New generation antibodiesZooMAb® antibodies can help researchers to go further than ever before while reducing the use of animalsDIVE DEEPER
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Do you believe in a future where medicine will meet everyone’s needs? By joining the team working to develop personalized medicine or coming aboard any of our other numerous research teams, you can be sure of one thing: Your career with us will be anything but standard.View All Jobs Join our Talent Zone
 Genomics examines a person’s DNA blueprint; metabolomics involves looks at small molecules (metabolites); proteomics - explores protein molecules; and transcriptomics examines gene activity.